SSA/Ro60 antibodies

Indication

SSA/Ro60 antibodies are included in the analysis ENA screen. See therefore “ENA screen” for indication, method, answer and reference range.

Interpretation

Positive in about 70% of patients with primary Sjögren’s syndrome and in 10-15% of patients with secondary Sjögren’s syndrome. 40% of patients with SLE are positive for SSA. Other disease associations are also described, e.g. scleroderma and MCTD. Positive anti-SSA also occurs in malaria, bilharzia and leishmaniasis.

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20 years experience