Ribosomal RNP (rRNP and P-protein) antibodies

Indication

Suspicion of systemic lupus erythematosus, especially with CNS involvement.

Method

ELISA with purified proteins. The antibodies react with three phosphoproteins of 38, 19 and 17 kD, which are all bound to ribosomal RNA.

Answer

The result is given as positive or negative.

Interpretation

Positive in about 10% of patients with systemic lupus erythematosus, especially in lupus manifestations in the central nervous system.

Read more about sampling

 

Acute test