Purkinje cell antibodies (PCA 2)

Indication

Suspicion of paraneoplastic syndrome.

Method

Indirect immunofluorescence.

Answer

The result is given as negative or positive with titer.

Interpretation

The antigen PCA-2 (Purkinje cell antigen 2) is found in Purkinje cells, most major neurons and several tumour types, e.g. breast, ovary and SCLC. They often present as encephalomyelitis or cerebellar degeneration.

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Packages and other tests

View other packages Paraneoplastic Syndromes and Limbic Encephalitis (560, 561 and 562)

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