Gliadin antibodies – IgA

Indication

Suspicion of coeliac disease (CD) or dermatitis herpetiformis.

Method

ELISA with gliadin as antigen.

Interpretation

IgA anti-gliadin is positive in approximately 95% of patients with untreated celiac disease. IgG anti-gliadin have lower sensitivity, about 50%, and is not as specific as IgA anti-gliadin in celiac disease, but may be important in the diagnosis of patients with IgA deficiency. The antibodies disappear during gluten-free diet and are not found in healthy people. Recommended tests in cases of suspected gluteninducerad enteropathy includes ncluded along with anti-endomysium and anti-transglutaminase. Positive results for IgA  anti-gliadin antibodies stronlgy indicates celiac diagnosis, but the final diagnosis must be based on examination of the small bowel biopsy and clinical remission during gluten free diet.

Read more about sampling

Packages and other tests

View other packages Coeliac disease (512)

Clinical studies